Published 5 Feb 2026
We proudly announce that our Aspen API colleague, Nick Zilverschoon will be presenting on FAST 2026:
“Isolation and identification of unknowns and purification of APIs using preparative HPLC”
At Aspen we strive to keep up with the latest analytical developments for all our CDMO solutions. Therefore, we are happy our Aspen colleague, Maria Baltussen, is on the FAST (Forum for Analytical Science and Technology) organizing committee, a scientific conference for analytical science. FAST is a part of TI-COAST (Top Institute for Comprehensive Analytical Science and Technology), shortly COAST an independent foundation setting out to innovate analytical science and technology and its education.
FAST 2026 brings together experts from industry and academia to network and discuss new developments. Aspen API colleague, Nick Zilverschoon will be presenting: “Isolation and identification of unknowns and purification of APIs using preparative HPLC” on Day 2 of FAST 2026 February 27th.
At Aspen API high-quality active pharmaceutical ingredients (APIs) are produced. During the synthesis of these compounds, unknown impurities may form and their structure must be elucidated to optimize the process. Preparative HPLC is used as a tool to collect fractions for structure elucidation by MS and NMR. In addition, preparative HPLC is a tool to purify synthetic peptides. Aspen strives to design purification processes of peptides resulting in a >99.0% purity. In this presentation two case studies will be presented where 1) a steroid related impurity was isolated and 2) a purification process of a synthetic peptide was developed and scaled-up.
